SCHEMBL27835342

SCHEMBL27835342

NC(=O)NSCC1CCCO1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 4/20 0.41
TP53 P04637 1/20 0.41
ALOX12 P18054 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
HTT P42858 1/20 0.40
LMNA P02545 2/20 0.39
POLB P06746 1/20 0.39
MCL1 Q07820 1/20 0.38
ANPEP P15144 1/20 0.38
APEX1 P27695 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14744490 0.74
SCHEMBL2561552 0.74
SCHEMBL14744489 0.74
SCHEMBL30223355 0.73 SMN1; SMN2 (0.64) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL4812101 0.73 SMN1; SMN2 (0.64) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL30223215 0.73 SMN1; SMN2 (0.64) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL27681841 0.71 EPHX1 (0.47) HPGDKMT2A
SCHEMBL2825060 0.69 HPGD (0.50) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL21378709 0.69 HPGD (0.50) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL21378707 0.69 HPGD (0.50) USP2SMN1; SMN2HPGDTP53ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101925300-A Novel compounds as cannabinoid receptor ligands and uses thereof ABBOTT LAB 2010-12-22 CN disclosed