Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046444 | 0.97 | HCAR2 (0.52) | HCAR2LMNAALDH1A1ESR1CHRM1 | |
| SCHEMBL52299 | 0.97 | — | — | |
| Bicarbonate SCHEMBL301508 | 0.95 | HCAR2 (0.46) | HCAR2LMNAALDH1A1ESR1CHRM1 | |
| Butane SCHEMBL5275061 | 0.94 | HCAR2 (0.50) | HCAR2LMNAALDH1A1ESR1CHRM1 | |
| Fluoride SCHEMBL27522001 | 0.94 | — | — | |
| SCHEMBL4698697 | 0.94 | — | — | |
| SCHEMBL27838387 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL11851759 | 0.94 | — | — | |
| SCHEMBL7007667 | 0.94 | — | — | |
| SCHEMBL4665157 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118336122-A | Electrolyte and sodium ion battery for stabilizing lamellar positive electrode by synergistic action of nitrile cosolvent and double salts | 河北工业大学 | 2024-07-12 | — | — | CN | claimed |
| CN-116682942-A | Preparation method of electrode plate | 北京车和家汽车科技有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-116868417-B | Battery and electricity utilization device | 宁德时代新能源科技股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118336122-A | Electrolyte and sodium ion battery for stabilizing lamellar positive electrode by synergistic action of nitrile cosolvent and double salts | 河北工业大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-112655110-B | Separator and electrochemical device including the same | 株式会社LG新能源 | 2024-07-05 | — | — | CN | disclosed |
| CN-118299525-A | Negative electrode active material, preparation method and application | 宁德时代新能源科技股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-12027724-B2 | Method for manufacturing separator for electrochemical device | LG ENERGY SOLUTION, LTD. (KR) | 2024-07-02 | — | — | US | disclosed |
| WO-2024136198-A1 | METHOD FOR PREPARING POSITIVE ELECTRODE ACTIVE MATERIAL PRECURSOR, POSITIVE ELECTRODE ACTIVE MATERIAL PRECURSOR, AND METHOD FOR PREPARING POSITIVE ELECTRODE ACTIVE MATERIAL USING POSITIVE ELECTRODE ACTIVE MATERIAL PRECURSOR | 주식회사 엘지화학 | 2024-06-27 | — | — | WO | disclosed |
| WO-2024128853-A1 | ELECTRODE ASSEMBLY AND SECONDARY BATTERY COMPRISING SAME | 주식회사 엘지에너지솔루션 | 2024-06-20 | — | — | WO | disclosed |
| CN-115088128-B | Separator for lithium secondary battery and method for manufacturing the same | 株式会社LG新能源 | 2024-06-11 | — | — | CN | disclosed |
| CN-118160112-A | Positive electrode material composition, preparation method thereof, positive electrode sheet comprising positive electrode material composition, secondary battery and electric device | 宁德时代新能源科技股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20050175900-A1 | High energy density; long life; current collector having tin metal or alloy and aluminum metal or alloy layers covered by metal having low capability of intercalculating with lithium | MITSUI MINING & SMELTING COMPANY, LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| US-20050069769-A1 | binder containing a polymer of acrylonitrile or methacrylonitrile- 1-olefin-acrylic or methacrylic ester wihich is dissolved in the liquid medium | ZEON CORPORATION (JP) | 2005-03-31 | — | — | US | disclosed |
| EP-1501136-A1 | NEGATIVE ELECTRODE FOR NON-AQUEOUS ELECTROLYTE SECONDARY CELL AND METHOD FOR MANUFACTURE THEREOF, AND NON-AQUEOUS ELECTROLYTE SECONDARY CELL | Mitsui Mining & Smelting Co., Ltd. (JP) | 2005-01-26 | — | — | EP | disclosed |
| US-20040185347-A1 | Non-aqueous electrolyte and a lithium secondary battery comprising the same | SAMSUNG SDI CO., LTD. (KR) | 2004-09-23 | — | — | US | disclosed |
| EP-1458048-A1 | A non-aqueous electrolyte and a lithium secondary battery comprising the same | Samsung SDI Co., Ltd. (KR) | 2004-09-15 | — | — | EP | disclosed |
| US-20040020763-A1 | Slurry composition for secondary cell positive electrode, secondary cell positive electrode and secondary cell | ZEON CORPORATION (JP) | 2004-02-05 | — | — | US | disclosed |
| EP-1363346-A2 | Gel electrolyte, process for producing the same, and use thereof | NITTO DENKO CORPORATION (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-20030207179-A1 | Gel electrolyte, process for producing the same, and use thereof | NITTO DENKO CORPORATION | 2003-11-06 | — | — | US | disclosed |
| EP-0967233-A1 | Polymers from block copolymerisable monomers and their use e.g. for the preparation of ionic conductors | HYDRO-QUEBEC (CA) | 1999-12-29 | — | — | EP | disclosed |