SCHEMBL2784079

SCHEMBL2784079

Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)c2cc3c(C(O)(C(F)(F)F)C(F)(F)F)cc(C(O)(C(F)(F)F)C(F)(F)F)c(N)c3cc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.61
▸ KMT2A Q03164 3/20 0.61
▸ KDM4E B2RXH2 2/20 0.61
▸ MAPT P10636 2/20 0.61
▸ SMN1; SMN2 Q16637 2/20 0.61
▸ MAPK1 P28482 2/20 0.61
▸ LMNA P02545 1/20 0.61
▸ HTT P42858 1/20 0.61
▸ NPSR1 Q6W5P4 1/20 0.61
▸ HSD17B10 Q99714 2/20 0.51
▸ ALDH1A1 P00352 1/20 0.51
▸ GLA P06280 1/20 0.51
▸ POLB P06746 1/20 0.51
▸ GAA P10253 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ ATM Q13315 1/20 0.51
▸ KCNJ11 Q14654 13/20 0.34
▸ ABCC9 O60706 5/20 0.33
▸ ABCC8 Q09428 5/20 0.33
▸ KCNJ8 Q15842 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2784727 0.90 SMN1; SMN2 (0.55) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2783792 0.88 MEN1 (0.70) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2785789 0.86 KDM4E (0.59) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2784774 0.86 KDM4E (0.58) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2783871 0.84 KDM4E (0.54) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2785172 0.84 KDM4E (0.54) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2784634 0.81 MEN1 (0.62) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2785734 0.81 MEN1 (0.62) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2783169 0.81 SMN1; SMN2 (0.54) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL2784209 0.81 SMN1; SMN2 (0.54) MEN1KMT2AKDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130085237-A1 Fluorinated Diamine and Polymer Formed Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2013-04-04 — — US disclosed
US-20100029895-A1 Fluorinated Diamine and Polymer Formed Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2010-02-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029895-A1 Fluorinated Diamine and Polymer Formed Therefrom AFF2, AFF1, AFF4 MEN1 2546/4885KMT2A 662/4885KDM4E 1841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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