Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27840960 | 0.82 | PIK3CA (0.57) | PIK3CAALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL27841038 | 0.82 | PIK3CA (0.65) | PIK3CAALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL28795809 | 0.78 | PIK3CA (0.66) | PIK3CAALDH1A1RXFP1L3MBTL1MEN1 | |
| SCHEMBL27858464 | 0.77 | PIK3CA (0.69) | PIK3CAALDH1A1MEN1KMT2APIK3CD | |
| SCHEMBL28795786 | 0.77 | PIK3CA (0.69) | PIK3CAALDH1A1MEN1KMT2APIK3CD | |
| SCHEMBL23876431 | 0.74 | MEN1 (0.66) | PIK3CAALDH1A1MEN1KMT2APIK3CD | |
| SCHEMBL27840967 | 0.71 | PIK3CA (0.69) | PIK3CAALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL14301180 | 0.70 | MEN1 (0.56) | PIK3CAALDH1A1MEN1KMT2APIK3CD | |
| SCHEMBL1794443 | 0.70 | MEN1 (0.73) | PIK3CAALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL27819107 | 0.70 | PIK3CA (0.54) | PIK3CAALDH1A1MEN1KMT2APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250022-B | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2013-10-16 | — | — | CN | claimed |
| CN-102250022-A | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2011-11-23 | — | — | CN | claimed |
| CN-102250022-B | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2013-10-16 | — | — | CN | disclosed |
| CN-102250022-A | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2011-11-23 | — | — | CN | disclosed |