SCHEMBL27845347

SCHEMBL27845347

O=C(O)CCC(=O)OS(=O)(=O)C(CC(=O)O)C(=O)O.[KH]

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.34
EGLN1 Q9GZT9 2/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
LMNA P02545 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.32
SUCNR1 Q9BXA5 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
APEX1 P27695 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27519071 0.96 FOLH1 (0.34) FOLH1EGLN1KDM6BKDM5CPHF8
Ammonia Solution, Strong SCHEMBL27490054 0.96 TDP1 (0.35) FOLH1EGLN1KDM6BKDM5CPHF8
SCHEMBL27678101 0.96 FOLH1 (0.34) FOLH1EGLN1KDM6BKDM5CPHF8
SCHEMBL27696676 0.96 FOLH1 (0.34) FOLH1EGLN1KDM6BKDM5CPHF8
SCHEMBL27881532 0.96 TDP1 (0.33) FOLH1TDP1SMN1; SMN2
SCHEMBL8345802 0.94 TDP1 (0.34) FOLH1TDP1SMN1; SMN2
SCHEMBL11065997 0.93 TDP1 (0.33) FOLH1TDP1SMN1; SMN2
SCHEMBL28189251 0.93 TDP1 (0.33) FOLH1TDP1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL27832597 0.93 TDP1 (0.38) FOLH1TDP1SMN1; SMN2
SCHEMBL28008451 0.87 TSHR (0.35) FOLH1LMNATDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102341227-A Aqueous coating agent AUTOLIV DEV 2012-02-01 CN disclosed