Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18252787 | 0.93 | PTGS1 (0.73) | PTGS1PTGS2HTTAOC3CRHBP | |
| SCHEMBL27598809 | 0.89 | PTGS1 (0.63) | PTGS1PTGS2NPSR1HPGD | |
| SCHEMBL15887347 | 0.88 | PTGS1 (0.81) | PTGS1PTGS2HTTAOC3CRHBP | |
| SCHEMBL1056332 | 0.88 | PTGS1 (1.00) | PTGS1PTGS2HTTAOC3CRHBP | |
| SCHEMBL22390806 | 0.86 | PTGS1 (0.73) | PTGS1PTGS2HTTAOC3CRHBP | |
| SCHEMBL18252774 | 0.84 | PTGS1 (0.61) | PTGS1PTGS2NPSR1HPGD | |
| SCHEMBL19286773 | 0.83 | PTGS1 (0.69) | PTGS1PTGS2HTTAOC3CRHBP | |
| SCHEMBL29903947 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2 | |
| SCHEMBL4132153 | 0.81 | PTGS1 (0.66) | PTGS1PTGS2HTTAOC3CYP1A2 | |
| SCHEMBL17541509 | 0.79 | PTGS1 (0.64) | PTGS1PTGS2HTTAOC3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341494-B | Transaminase polypeptides | CODEXIS, INC. (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-102341494-A | TRANSAMINASE POLYPEPTIDES | CODEXIS INC | 2012-02-01 | — | — | CN | disclosed |