Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 10/20 | 0.60 |
| ▸ | CPT1B | Q92523 | 9/20 | 0.60 |
| ▸ | CPT2 | P23786 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848105 | 0.92 | CPT1A (0.57) | CPT1ACPT1BCPT2POLBCYP2C9 | |
| SCHEMBL27865245 | 0.91 | CPT1A (0.63) | CPT1ACPT1BCPT2CYP2C9LMNA | |
| SCHEMBL27715640 | 0.87 | CPT1A (0.75) | CPT1ACPT1BCPT2LMNAMAPT | |
| SCHEMBL751492 | 0.86 | CPT1A (0.80) | CPT1ACPT1BCPT2RORC | |
| SCHEMBL27731306 | 0.83 | CPT1A (0.59) | CPT1ACPT1BCPT2CYP2C9LMNA | |
| SCHEMBL27848106 | 0.80 | CPT1A (0.56) | CPT1ACPT1BCPT2CYP2C9LMNA | |
| SCHEMBL28796755 | 0.80 | CPT1A (0.74) | CPT1ACPT1BCPT2MAPTSMN1; SMN2 | |
| SCHEMBL755717 | 0.79 | CPT1A (0.76) | CPT1ACPT1BCPT2MAPTRORC | |
| SCHEMBL755030 | 0.77 | CPT1A (0.64) | CPT1ACPT1BCPT2CYP2C9LMNA | |
| SCHEMBL750135 | 0.76 | CPT1A (0.85) | CPT1ACPT1BCPT2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379044-B | Heterobicyclic sulfonamide derivatives for the treatment of diabetes | HOFFMANN LA ROCHE | 2012-04-11 | — | — | CN | disclosed |