Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 19/20 | 0.71 |
| ▸ | CPT2 | P23786 | 9/20 | 0.71 |
| ▸ | CPT1B | Q92523 | 17/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775512 | 0.86 | CPT1A (0.64) | CPT1ACPT2CPT1B | |
| SCHEMBL27731313 | 0.86 | CPT1A (0.62) | CPT1ACPT2CPT1BCYP2C9 | |
| SCHEMBL28796755 | 0.84 | CPT1A (0.74) | CPT1ACPT2CPT1B | |
| SCHEMBL750406 | 0.83 | CPT1A (0.80) | CPT1ACPT2CPT1BCYP2C9 | |
| SCHEMBL753150 | 0.83 | CPT1A (1.00) | CPT1ACPT2CPT1B | |
| SCHEMBL750308 | 0.78 | CPT1A (1.00) | CPT1ACPT2CPT1B | |
| SCHEMBL753546 | 0.76 | CYP2C9 (0.71) | CPT1ACPT2CPT1BCYP2C9 | |
| SCHEMBL27731306 | 0.76 | CPT1A (0.59) | CPT1ACPT2CPT1BCYP2C9 | |
| SCHEMBL755737 | 0.74 | CPT1A (0.74) | CPT1ACPT2CPT1B | |
| SCHEMBL755026 | 0.74 | CPT1A (0.80) | CPT1ACPT2CPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379044-B | Heterobicyclic sulfonamide derivatives for the treatment of diabetes | HOFFMANN LA ROCHE | 2012-04-11 | — | — | CN | disclosed |