Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676599 | 0.89 | MAPT (0.51) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL31226878 | 0.89 | MAPT (0.54) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL9848801 | 0.89 | MAPT (0.54) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL9848805 | 0.89 | MAPT (0.54) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL9848797 | 0.89 | MAPT (0.54) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL28706418 | 0.88 | MAPT (0.53) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL665500 | 0.88 | MAPT (0.47) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL9848816 | 0.87 | CYP26A1 (0.60) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL666435 | 0.87 | MAPT (0.49) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL1374453 | 0.87 | CYP26A1 (0.60) | MAPTSMN1; SMN2ALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102317269-A | Novel amino aza heterocyclic carboxamides | MERCK PATENT GMBH | 2012-01-11 | — | — | CN | disclosed |