SCHEMBL278488

SCHEMBL278488

O=[N+]([O-])c1ccc(Cl)c(Cl)c1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 1.00
TSHR P16473 2/20 0.54
MAPK1 P28482 1/20 0.54
VCAM1 P19320 7/20 0.47
GPR35 Q9HC97 1/20 0.47
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 1/20 0.45
HTR2A P28223 2/20 0.44
HTR2C P28335 2/20 0.44
HTR2B P41595 2/20 0.44
PDE7A Q13946 1/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28391943 0.90 TDP1 (0.81) TDP1TSHRMAPK1VCAM1GPR35
Toluene SCHEMBL28713353 0.85 TDP1 (0.72) TDP1TSHRMAPK1VCAM1ALDH1A1
SCHEMBL11811233 0.83 TDP1 (0.71) TDP1TSHRMAPK1VCAM1GPR35
SCHEMBL29918148 0.82 TDP1 (0.69) TDP1TSHRMAPK1VCAM1ALDH1A1
SCHEMBL2145586 0.82 TDP1 (0.69) TDP1TSHRMAPK1VCAM1ALDH1A1
SCHEMBL2160036 0.82 TDP1 (0.69) TDP1TSHRMAPK1VCAM1GPR35
SCHEMBL25343446 0.80 TDP1 (0.67) TDP1TSHRMAPK1VCAM1ALDH1A1
SCHEMBL5374994 0.80 TDP1 (0.67) TDP1TSHRMAPK1VCAM1GPR35
SCHEMBL2910425 0.80 TDP1 (0.67) TDP1TSHRMAPK1VCAM1ALDH1A1
SCHEMBL4748225 0.80 TDP1 (0.67) TDP1TSHRMAPK1VCAM1GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432011-A Low-dielectric epoxy resin for copper-clad plate and processing technology thereof 江苏耀鸿电子有限公司 2025-02-14 CN claimed
CN-115845919-B Nitrogen-doped phenolic resin embedded nickel porous carbon coated honeycomb ceramic monolithic catalyst 浙江工业大学 2024-07-19 CN claimed
CN-114230471-B Preparation method of 3, 4-dichloro-2-fluoroaniline 河北科技大学 2024-01-26 CN claimed
CN-114349647-B Synthesis method of aclonifen 陕西菲尔特化工有限公司 2024-01-09 CN claimed
CN-116983240-A Toothpaste capable of efficiently removing dental calculus and preparation method thereof 广州泓汇日化科技有限公司 2023-11-03 CN claimed
CN-116836060-A Preparation method of 2,3, 4-trifluoro nitrobenzene 山东京博农化科技股份有限公司 2023-10-03 CN claimed
CN-114805078-B Method for preparing 2,3, 4-trichloronitrobenzene through microchannel nitration 上海农帆生物科技有限公司 2023-09-29 CN claimed
CN-115353458-B Method for preparing aclonifen 上海农帆生物科技有限公司 2023-09-29 CN claimed
CN-115845919-A Nitrogen-doped phenolic resin inlaid nickel porous carbon coated honeycomb ceramic monolithic catalyst 浙江工业大学 2023-03-28 CN claimed
CN-115353458-A Method for preparing aclonifen 上海农帆生物科技有限公司 2022-11-18 CN claimed
US-5104491-A Method for purifying pentachloronitrobenzene by solid base treatment MITSUI TOATSU CHEMICALS, INC. (JP) 1992-04-14 US claimed
EP-0448347-A2 Pigment composition NIPPON PAINT CO., LTD. (JP) 1991-09-25 EP claimed
US-5012015-A Nitrading a trichlorobenzene with mixed acid, hydrolysis DAIEI CHEMICAL CO., LTD. (JP) 1991-04-30 US claimed
EP-0415158-A2 Process for the preparation of chlorine substituted aromatic amines BAYER AG (DE) 1991-03-06 EP claimed
EP-0252352-A2 Highly soluble antibacterially active organic salts of pyridobenzothiazines and their preparation process MEDIOLANUM FARMACEUTICI S.P.A. (IT) 1988-01-13 EP claimed
CN-86103819-A The fungicidal composition of synergy 1987-02-04 CN claimed
EP-0089517-B1 PROCESS FOR THE PREPARATION OF DIPHENYL ETHERS CELAMERCK GmbH & Co. KG (DE) 1986-06-11 EP claimed
EP-0089517-A1 Process for the preparation of diphenyl ethers CELAMERCK GmbH & Co. KG (DE) 1983-09-28 EP claimed
US-4375550-A Hydrogenation of halogen-substituted aromatic nitro compounds JOHNSON, MATTHEY & CO., LIMITED (GB) 1983-03-01 US claimed
US-4124768-A Process for preparing pure substituted 2,5-diarylamino-terephthalates and the corresponding free acids HOECHST AKTIENGESELLSCHAFT 1978-11-07 US claimed