Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180613 | 0.96 | CYP4F2 (0.50) | CYP4F2CYP4A11HDAC1HDAC6CNR1 | |
| SCHEMBL9120700 | 0.90 | POLB (0.50) | CYP4F2CYP4A11HDAC1HDAC6CNR1 | |
| SCHEMBL27866945 | 0.88 | HDAC1 (0.50) | HDAC1HDAC6CNR1CNR2PPARA | |
| SCHEMBL20945413 | 0.88 | HDAC1 (0.56) | CYP4F2CYP4A11HDAC1HDAC6CNR1 | |
| SCHEMBL3168986 | 0.87 | CYP2D6 (0.48) | HDAC1HDAC6CNR1CNR2PPARA | |
| SCHEMBL8350949 | 0.86 | PPARA (0.61) | CYP4F2CYP4A11HDAC1HDAC6PPARA | |
| SCHEMBL7421760 | 0.86 | CYP4F2 (0.52) | CYP4F2CYP4A11HDAC1HDAC6CNR1 | |
| SCHEMBL11817709 | 0.85 | TSHR (0.50) | POLBMTNR1AMTNR1B | |
| SCHEMBL28569142 | 0.84 | CNR1 (0.58) | HDAC1HDAC6CNR1CNR2PPARA | |
| SCHEMBL28589342 | 0.83 | CYP2D6 (0.61) | CNR1CNR2PPARAPPARGCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |