Bromide

Bromide

SCHEMBL2785247

[Br-].c1ccc(COCCCCCCCCCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 8/20 0.49
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 1/20 0.45
HIF1A Q16665 1/20 0.45
HRH4 Q9H3N8 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43
GBA1 P04062 2/20 0.42
UGCG Q16739 2/20 0.42
GBA2 Q9HCG7 2/20 0.42
TRAP1 Q12931 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL5359051 1.00 CHRNA7 (0.49) CHRNA7TDP1L3MBTL1TSHRHIF1A
Bromide SCHEMBL31020367 1.00 CHRNA7 (0.49) CHRNA7TDP1L3MBTL1TSHRHIF1A
Bromide SCHEMBL5618410 1.00 CHRNA7 (0.49) CHRNA7TDP1L3MBTL1TSHRHIF1A
Bromide SCHEMBL20120670 1.00 CHRNA7 (0.49) CHRNA7TDP1L3MBTL1TSHRHIF1A
Bromide SCHEMBL1518997 1.00 CHRNA7 (0.49) CHRNA7TDP1L3MBTL1TSHRHIF1A
Bromide SCHEMBL1244421 1.00 CHRNA7 (0.49) CHRNA7TDP1L3MBTL1TSHRHIF1A
SCHEMBL31342768 0.98 CHRNA7 (0.50) CHRNA7TDP1L3MBTL1TSHRHIF1A
Bromide SCHEMBL20488683 0.98 CHRNA7 (0.48) CHRNA7TDP1L3MBTL1TSHRHIF1A
Iodide SCHEMBL19032482 0.97 CHRNA7 (0.52) CHRNA7TDP1L3MBTL1TSHRHIF1A
Iodide SCHEMBL19032413 0.97 CHRNA7 (0.52) CHRNA7TDP1L3MBTL1TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010128038-A1 HYDROQUINONE DERIVATIVES AXOGLIA THERAPEUTICS S.A. (LU) 2010-11-11 WO disclosed