⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3930447 | 0.76 | — | — | |
| SCHEMBL27857168 | 0.74 | — | — | |
| Cadaverine Tartrate SCHEMBL22076336 | 0.72 | TSHR (0.77) | — | |
| Cadaverine Tartrate SCHEMBL28074990 | 0.72 | TSHR (0.77) | — | |
| Cadaverine Tartrate SCHEMBL25307085 | 0.71 | TSHR (0.91) | — | |
| Cadaverine Tartrate SCHEMBL24914 | 0.71 | TSHR (0.91) | — | |
| Cadaverine Tartrate SCHEMBL3165960 | 0.71 | TSHR (0.91) | — | |
| Cadaverine Tartrate SCHEMBL1764683 | 0.71 | TSHR (0.91) | — | |
| Cadaverine Tartrate SCHEMBL3165957 | 0.71 | TSHR (0.91) | — | |
| Cadaverine Tartrate SCHEMBL14742964 | 0.71 | TSHR (0.91) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837685-A | PSEUDOMYCIN | RESEARCH AND DEVELOPMENT INSTITUTE INC. AT MONTANA STATE UNIVERSITY (US) | 1998-11-17 | — | — | US | claimed |
| US-5576298-A | PSEUDOMYCIN | RESEARCH AND DEVELOPMENT INSTITUTE, INC. AT MONTANA STATE UNIVERSITY (US) | 1996-11-19 | — | — | US | claimed |
| US-7778779-B2 | Method of identifying a chemical entity which is a hydroxylase modulator | ISIS INNOVATION LIMITED (GB) | 2010-08-17 | — | — | US | disclosed |
| EP-2156830-A1 | Modulators of asparaginyl hydoxylase activity of FIH | ISIS INNOVATION LIMITED (GB) | 2010-02-24 | — | — | EP | disclosed |
| EP-1554394-B1 | Screening methods using a structural model of FIH | ISIS INNOVATION (GB) | 2009-12-16 | — | — | EP | disclosed |
| US-20070048728-A1 | Hydroxylases and modulators thereof | ISIS INNOVATION LIMITED (GB) | 2007-03-01 | — | — | US | disclosed |
| EP-1554394-A2 | ASPARAGINYL HYDROXYLASES AND MODULATORS THEREOF | ISIS INNOVATION LIMITED (GB) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004035812-A2 | ASPARAGINYL HYDROXYLASES AND MODULATORS THEREOF | ISIS INNOVATION LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |