Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14875 | 0.87 | — | — | |
| SCHEMBL30363554 | 0.87 | TSHR (1.00) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL21630258 | 0.87 | TSHR (1.00) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene SCHEMBL8850416 | 0.85 | TSHR (0.95) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2457464 | 0.85 | — | — | |
| Ethylene SCHEMBL2946941 | 0.85 | TSHR (0.95) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene Glycol SCHEMBL8650028 | 0.85 | TSHR (0.95) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene SCHEMBL4213298 | 0.85 | TSHR (0.95) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene SCHEMBL259312 | 0.85 | TSHR (0.95) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene SCHEMBL8048018 | 0.85 | TSHR (0.95) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638538-A | Al/HMX/neutral macromolecular bonding agent compound and preparation method thereof | 西安近代化学研究所 | 2025-03-18 | — | — | CN | claimed |
| CN-115974629-B | Low-sensitivity high-strength HMX-based composite material, preparation method and application thereof | 西安近代化学研究所 | 2024-05-28 | — | — | CN | claimed |
| CN-116041124-B | Poly (hydroxyethyl acrylate) nitrate modified CL-20-based composite material, preparation method and application | 西安近代化学研究所 | 2024-01-02 | — | — | CN | claimed |
| CN-115160487-B | Neutral macromolecular bonding agent, preparation method, application and solid propellant | 西安近代化学研究所 | 2023-06-09 | — | — | CN | claimed |
| CN-116041124-A | Poly (hydroxyethyl acrylate) nitrate modified CL-20-based composite material, preparation method and application | 西安近代化学研究所 | 2023-05-02 | — | — | CN | claimed |
| CN-115974629-A | Low-sensitivity high-strength HMX-based composite material, and preparation method and application thereof | 西安近代化学研究所 | 2023-04-18 | — | — | CN | claimed |
| CN-115160487-A | Neutral macromolecular bonding agent, preparation method and application thereof, and solid propellant | 西安近代化学研究所 | 2022-10-11 | — | — | CN | claimed |
| CN-119638538-B | Al/HMX/neutral macromolecular bonding agent compound and preparation method thereof | 西安近代化学研究所 | 2025-11-11 | — | — | CN | disclosed |
| CN-119638538-A | Al/HMX/neutral macromolecular bonding agent compound and preparation method thereof | 西安近代化学研究所 | 2025-03-18 | — | — | CN | disclosed |
| CN-119638538-A | Al/HMX/neutral macromolecular bonding agent compound and preparation method thereof | 西安近代化学研究所 | 2025-03-18 | — | — | CN | disclosed |
| CN-115974629-B | Low-sensitivity high-strength HMX-based composite material, preparation method and application thereof | 西安近代化学研究所 | 2024-05-28 | — | — | CN | disclosed |
| CN-115974629-B | Low-sensitivity high-strength HMX-based composite material, preparation method and application thereof | 西安近代化学研究所 | 2024-05-28 | — | — | CN | disclosed |
| CN-116041124-B | Poly (hydroxyethyl acrylate) nitrate modified CL-20-based composite material, preparation method and application | 西安近代化学研究所 | 2024-01-02 | — | — | CN | disclosed |
| CN-116041124-A | Poly (hydroxyethyl acrylate) nitrate modified CL-20-based composite material, preparation method and application | 西安近代化学研究所 | 2023-05-02 | — | — | CN | disclosed |
| CN-116041124-A | Poly (hydroxyethyl acrylate) nitrate modified CL-20-based composite material, preparation method and application | 西安近代化学研究所 | 2023-05-02 | — | — | CN | disclosed |
| CN-115974629-A | Low-sensitivity high-strength HMX-based composite material, and preparation method and application thereof | 西安近代化学研究所 | 2023-04-18 | — | — | CN | disclosed |
| CN-115974629-A | Low-sensitivity high-strength HMX-based composite material, and preparation method and application thereof | 西安近代化学研究所 | 2023-04-18 | — | — | CN | disclosed |
| CN-115160487-A | Neutral macromolecular bonding agent, preparation method and application thereof, and solid propellant | 西安近代化学研究所 | 2022-10-11 | — | — | CN | disclosed |
| CN-115160487-A | Neutral macromolecular bonding agent, preparation method and application thereof, and solid propellant | 西安近代化学研究所 | 2022-10-11 | — | — | CN | disclosed |
| CN-102245724-A | Chemical mechanical polishing solution | ANJI MICROELECTRONICS SHANGHAI | 2011-11-16 | — | — | CN | disclosed |