Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.66 |
| ▸ | S1PR3 | Q99500 | 15/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.62 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.62 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1226622 | 1.00 | S1PR1 (0.66) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL1226619 | 1.00 | S1PR1 (0.66) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL1226614 | 1.00 | S1PR1 (0.66) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL1227287 | 0.91 | S1PR1 (0.66) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL1227279 | 0.91 | S1PR1 (0.66) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL1227283 | 0.91 | S1PR1 (0.66) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL27876340 | 0.91 | S1PR1 (0.66) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL1225710 | 0.91 | S1PR1 (0.67) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL1225704 | 0.91 | S1PR1 (0.67) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL1225701 | 0.91 | S1PR1 (0.67) | S1PR1S1PR3S1PR4S1PR5CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102548989-A | Sphingosine-1-phosphate receptor agonists | BRISTOL MYERS SQUIBB CO | 2012-07-04 | — | — | CN | claimed |
| CN-102548989-A | Sphingosine-1-phosphate receptor agonists | BRISTOL MYERS SQUIBB CO | 2012-07-04 | — | — | CN | disclosed |