Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27878887 | 0.89 | SCD (0.52) | SCDPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL27878888 | 0.86 | SCD (0.51) | SCDPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL1767431 | 0.75 | SCD (0.67) | SCDTP53KDM4E | |
| SCHEMBL14480121 | 0.73 | SCD (0.62) | SCDTP53ALDH1A1 | |
| SCHEMBL1576766 | 0.73 | HSD17B3 (0.51) | SCDPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL1576789 | 0.72 | HSD17B3 (0.50) | SCDPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL12717189 | 0.71 | HSD17B3 (0.48) | SCDPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL1577082 | 0.71 | SCD (0.53) | SCDPPARGPPARDPPARA | |
| SCHEMBL12717410 | 0.71 | SCD (0.49) | SCDTP53LMNA | |
| SCHEMBL27838041 | 0.70 | SCD (0.48) | SCDTP53ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574841-A | Pyrazole derivatives which modulate stearoyl-coa desaturase | NOVARTIS AG | 2012-07-11 | — | — | CN | claimed |
| CN-102574841-A | Pyrazole derivatives which modulate stearoyl-coa desaturase | NOVARTIS AG | 2012-07-11 | — | — | CN | disclosed |