Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60463 | 0.98 | — | — | |
| SCHEMBL11921 | 0.98 | — | — | |
| SCHEMBL11926 | 0.98 | — | — | |
| Iodide SCHEMBL29010172 | 0.95 | CYP1A2 (0.53) | CYP1A2ALDH1A1ADRA2AS1PR4S1PR1 | |
| Cyanide SCHEMBL30330146 | 0.91 | CYP1A2 (0.50) | CYP1A2ALDH1A1ADRA2AS1PR4S1PR1 | |
| SCHEMBL1760663 | 0.91 | CYP1A2 (0.64) | CYP1A2ALDH1A1ADRA2AS1PR1S1PR3 | |
| SCHEMBL3476022 | 0.91 | CYP1A2 (0.64) | CYP1A2ALDH1A1ADRA2AS1PR1S1PR3 | |
| SCHEMBL28122639 | 0.90 | CYP1A2 (0.48) | CYP1A2ALDH1A1ADRA2A | |
| Fluoride SCHEMBL30212759 | 0.89 | CYP1A2 (0.62) | CYP1A2ALDH1A1ADRA2AS1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL30330842 | 0.89 | CYP1A2 (0.62) | CYP1A2ALDH1A1ADRA2AS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102426920-A | Solar cell electrolyte as well as preparation method and application thereof | UNIV SOOCHOW | 2012-04-25 | — | — | CN | disclosed |