Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 9/20 | 0.49 |
| ▸ | CDK1 | P06493 | 9/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.49 |
| ▸ | GSK3A | P49840 | 9/20 | 0.49 |
| ▸ | GSK3B | P49841 | 9/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 9/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786754 | 0.80 | GSK3A (0.67) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL2785987 | 0.76 | MAPK14 (0.73) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL3327536 | 0.72 | DHODH (0.50) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL2789668 | 0.72 | NPC1 (0.46) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL1617354 | 0.70 | CCNB2 (0.46) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL27945860 | 0.69 | DHODH (0.51) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL1778575 | 0.67 | GSK3A (0.71) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL6246075 | 0.67 | MAPK14 (0.66) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL22477643 | 0.66 | MEN1 (0.50) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL13379720 | 0.66 | MAPK14 (0.45) | CCNB2CDK1CCNB1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | disclosed |