SCHEMBL27870237

SCHEMBL27870237

Nc1ncc(Br)nc1COC=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATR Q13535 1/20 0.32
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28629865 0.81
SCHEMBL28622068 0.81 MAPKAPK2 (0.41)
SCHEMBL28945973 0.81
SCHEMBL28946020 0.79 CCR4 (0.35)
SCHEMBL28051785 0.76
SCHEMBL28051809 0.76
SCHEMBL28369872 0.75 PLAU (0.32)
SCHEMBL27999901 0.74 MAPKAPK2 (0.31)
SCHEMBL29232167 0.73 MGMT (0.40)
SCHEMBL28066852 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113354631-A 1,3, 4-oxadiazole derivative and preparation method and application thereof 江苏大学 2021-09-07 CN claimed
CN-117946013-B Method for synthesizing 5, 6-dihalogen-3-aminopyrazine-2-methyl formate by one-pot method 白银康寓信生物科技有限公司 2024-07-02 CN disclosed
CN-115636796-B Preparation method of fampicin 新发药业有限公司 2024-06-18 CN disclosed
CN-117946013-A Method for synthesizing 5, 6-dihalogen-3-aminopyrazine-2-methyl formate by one-pot method 白银康寓信生物科技有限公司 2024-04-30 CN disclosed
CN-115636796-A Preparation method of Favipiravir 新发药业有限公司 2023-01-24 CN disclosed
CN-113354631-B 1,3,4-oxadiazole derivative and preparation method and application thereof 江苏大学 2022-11-18 CN disclosed
CN-113354631-A 1,3, 4-oxadiazole derivative and preparation method and application thereof 江苏大学 2021-09-07 CN disclosed
CN-111349049-A Favipiravir and synthesis process of intermediate thereof 江苏阿尔法药业有限公司 2020-06-30 CN disclosed
CN-106866553-B Synthesis method of Favipiravir 中南大学 2020-02-04 CN disclosed
CN-106478528-A The synthesis technique of Favipiravir 武汉工程大学 2017-03-08 CN disclosed
CN-104936953-B Compound (I) 阿斯利康(瑞典)有限公司 2017-03-08 CN disclosed
CN-102300862-B Compounds useful as inhibitors of ATR kinase 沃泰克斯药物股份有限公司 2016-11-23 CN disclosed
CN-106083745-A The synthetic method of 6 fluorine 3 hydroxyl 2 pyrazinamide 山东百诺医药股份有限公司 2016-11-09 CN disclosed
CN-105658639-A Alkynyl alcohols and methods of use 豪夫迈·罗氏有限公司 2016-06-08 CN disclosed
CN-102665718-B Heterocyclic compounds useful as PDK1 inhibitors MILLENNIUM PHARMACEUTICALS, INC. (US) 2016-03-09 CN disclosed
CN-102665718-A Heterocyclic compounds useful as pdk1 inhibitors BIOGEN IDEC INC 2012-09-12 CN disclosed