Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 1.00 |
| ▸ | MET | P08581 | 2/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | FRK | P42685 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.47 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786656 | 0.86 | MAPK14 (0.75) | MAPK14METMAPK13MAPK12MAPK11 | |
| SCHEMBL284987 | 0.82 | MAPK14 (1.00) | MAPK14METMAPK13MAPK12MAPK11 | |
| SCHEMBL2891806 | 0.80 | MAPK14 (0.67) | MAPK14METMAPK13MAPK12MAPK11 | |
| SCHEMBL2786882 | 0.76 | MAPK14 (0.67) | MAPK14METMAPK13MAPK12MAPK11 | |
| SCHEMBL1994242 | 0.75 | MAPK14 (1.00) | MAPK14METMAPK13MAPK12MAPK11 | |
| SCHEMBL6643643 | 0.75 | MAPK14 (1.00) | MAPK14METMAPK13MAPK12MAPK11 | |
| SCHEMBL6640941 | 0.75 | MAPK14 (1.00) | MAPK14METMAPK13MAPK12MAPK11 | |
| SCHEMBL6646016 | 0.74 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6646025 | 0.74 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7117573 | 0.72 | MAPK14 (0.64) | MAPK14METMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | claimed |
| WO-2010046215-A2 | DIAZA-INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-04-29 | — | — | WO | disclosed |