Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27870991 | 1.00 | AAK1 (0.40) | AAK1PAX8FFAR4GSK3BDYRK1A | |
| SCHEMBL1294210 | 0.96 | AAK1 (0.38) | AAK1PAX8FFAR4GSK3BDYRK1A | |
| SCHEMBL27887125 | 0.92 | AAK1 (0.36) | AAK1PAX8GSK3BDYRK1A | |
| SCHEMBL19690733 | 0.91 | AAK1 (0.35) | AAK1GSK3BDYRK1A | |
| SCHEMBL1293882 | 0.90 | AAK1 (0.36) | AAK1FFAR4 | |
| SCHEMBL1294208 | 0.89 | AAK1 (0.36) | AAK1FFAR4SCN9A | |
| SCHEMBL1293881 | 0.88 | AAK1 (0.35) | AAK1FFAR4 | |
| SCHEMBL1293879 | 0.88 | AAK1 (0.34) | AAK1GSK3BDYRK1ASCN9A | |
| SCHEMBL9980531 | 0.88 | AAK1 (0.36) | AAK1PAX8 | |
| SCHEMBL10182576 | 0.88 | AAK1 (0.37) | AAK1PAX8MCL1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712623-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-04-02 | — | — | CN | disclosed |
| CN-102712623-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-10-03 | — | — | CN | disclosed |
| CN-102686565-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-09-19 | — | — | CN | disclosed |