Biphenyl

Biphenyl

SCHEMBL27872149

C=CC(=O)OCC(CC)CCCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.76
ALDH1A1 P00352 6/20 0.59
CYP3A4 P08684 3/20 0.59
CA2 P00918 1/20 0.59
LMNA P02545 3/20 0.54
PRSS1 P07477 1/20 0.53
PRSS2 P07478 1/20 0.53
PRSS3 P35030 1/20 0.53
TDP1 Q9NUW8 2/20 0.52
MAPK1 P28482 3/20 0.51
ATM Q13315 1/20 0.48
HSD17B10 Q99714 1/20 0.47
HPGD P15428 1/20 0.43
RECQL P46063 1/20 0.41
THRB P10828 3/20 0.40
THRA P10827 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL8820576 0.92 TSHR (0.91) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL21295161 0.90 TSHR (0.72) TSHRALDH1A1CYP3A4CA2LMNA
Phthalic Acid SCHEMBL28001687 0.90 TSHR (0.72) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL491218 0.90 TSHR (0.72) TSHRALDH1A1CYP3A4CA2LMNA
Benzene SCHEMBL8735839 0.89 TSHR (0.85) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL31365383 0.89 TSHR (0.71) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL8656081 0.88 TSHR (0.74) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL4254222 0.88 TSHR (0.69) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL20609794 0.87 TSHR (1.00) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL14869 0.87 TSHR (1.00) TSHRALDH1A1CYP3A4CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471526-A Polymers comprising heterocyclic 3-membered ring compounds and iodine-containing compounds LANXESS DEUTSCHLAND GMBH 2012-05-23 CN disclosed