Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 18/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24835784 | 0.82 | CFB (0.42) | CFB | |
| SCHEMBL30109220 | 0.81 | BRD4 (0.39) | BRD4 | |
| SCHEMBL15173394 | 0.80 | CFB (0.45) | CFB | |
| SCHEMBL29761191 | 0.80 | CFB (0.45) | CFB | |
| SCHEMBL25648828 | 0.78 | HSD17B10 (0.39) | CFBBRD4 | |
| SCHEMBL15590525 | 0.76 | CFB (0.39) | CFB | |
| SCHEMBL26724141 | 0.76 | CFB (0.51) | CFB | |
| SCHEMBL31549623 | 0.75 | CFB (0.40) | CFB | |
| SCHEMBL24786828 | 0.75 | CFB (0.40) | CFB | |
| SCHEMBL25647648 | 0.75 | NQO2 (0.42) | CFBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4650351-A1 | INHIBITOR OF COMPLEMENT FACTOR B | Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd. (CN) | 2025-11-19 | — | — | EP | disclosed |
| EP-4504699-A1 | COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | Novartis AG (CH) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023187715-A1 | COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2023-10-05 | — | — | WO | disclosed |
| CN-112739691-A | TRK inhibitors as anticancer agents | 泰励生物科技（上海）有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-102718692-B | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2014-01-08 | — | — | CN | disclosed |
| CN-102718692-A | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2012-10-10 | — | — | CN | disclosed |