Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16074680 | 0.94 | TSHR (0.37) | TSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL30293825 | 0.94 | TSHR (0.37) | TSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL16675541 | 0.94 | TSHR (0.37) | TSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL8375838 | 0.91 | TSHR (0.35) | TSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL6861061 | 0.88 | TSHR (0.33) | TSHRTDP1ALDH1A1 | |
| SCHEMBL1900195 | 0.87 | TSHR (0.37) | TSHRTDP1ALDH1A1MAPK1LMNA | |
| SCHEMBL1535121 | 0.85 | TSHR (0.47) | TSHRTDP1ALDH1A1MAPK1LMNA | |
| SCHEMBL8652009 | 0.84 | — | — | |
| SCHEMBL110741 | 0.84 | — | — | |
| SCHEMBL285354 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403953-B1 | METHOD FOR STEREOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | CAMBREX IEP GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2226386-A1 | Method for stereoselective enzymatic reduction of keto compounds | IEP GmbH (DE) | 2010-09-08 | — | — | EP | disclosed |