Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.45 |
| ▸ | MC4R | P32245 | 4/20 | 0.43 |
| ▸ | CCR3 | P51677 | 3/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11994122 | 0.89 | HRH3 (0.57) | HRH3MC4RCCR3 | |
| SCHEMBL11968971 | 0.88 | HRH3 (0.52) | HRH3MC4RCCR3 | |
| SCHEMBL11968870 | 0.88 | MC4R (0.53) | HRH3MC4RCCR3SLC2A1 | |
| SCHEMBL11968882 | 0.88 | HRH3 (0.56) | HRH3MC4RCCR3 | |
| SCHEMBL11994090 | 0.88 | HRH3 (0.48) | HRH3MC4RCCR3L3MBTL3L3MBTL1 | |
| SCHEMBL1461311 | 0.86 | HRH3 (0.47) | HRH3MC4RCCR3L3MBTL3L3MBTL1 | |
| SCHEMBL11968820 | 0.85 | HRH3 (0.53) | HRH3MC4RSLC2A1 | |
| SCHEMBL11968978 | 0.85 | HRH3 (0.45) | HRH3MC4R | |
| SCHEMBL11968881 | 0.85 | HRH3 (0.49) | HRH3MC4RCCR3 | |
| SCHEMBL11968875 | 0.85 | HRH3 (0.47) | HRH3MC4RCCR3SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712587-A | Novel ethane diamine hepcidin antagonists | VIFOR INT AG | 2012-10-03 | — | — | CN | disclosed |