Methylpyrrolidone

Methylpyrrolidone

SCHEMBL27877902

CN1CCCC1=O.Clc1nc(Cl)nc(Cl)n1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.71
BRD2 P25440 1/20 0.71
INMT O95050 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
PIK3CD O00329 1/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
ALDH1A1 P00352 3/20 0.33
GAA P10253 3/20 0.33
MAPT P10636 3/20 0.33
PSMD14 O00487 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
SRD5A1 P18405 1/20 0.32
LMNA P02545 2/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpyrrolidone SCHEMBL27899870 0.87 BRD4 (0.85) BRD4BRD2INMTPIK3CDKMT2A
Methylpyrrolidone SCHEMBL5555743 0.87
Methylpyrrolidone SCHEMBL28759163 0.87 BRD4 (0.94) BRD4BRD2INMTPIK3CDKMT2A
Methylpyrrolidone SCHEMBL29239623 0.84
Methylpyrrolidone SCHEMBL28336748 0.84
Methylpyrrolidone SCHEMBL487 0.84
Methylpyrrolidone SCHEMBL5423326 0.84
Methylpyrrolidone SCHEMBL1255511 0.84 BRD4 (1.00) BRD4BRD2INMTPIK3CDKMT2A
Methylpyrrolidone SCHEMBL8055062 0.84 BRD4 (1.00) BRD4BRD2INMTPIK3CDKMT2A
Methylpyrrolidone SCHEMBL9634127 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102731422-B Preparation method of 6-(N,N-dihydroxyethyl)amino-2,4-dichloro-1,3,5-triazine UNIV FUJIAN TECHNOLOGY 2015-05-13 CN disclosed
CN-102731422-A Preparation method of 6-(N,N-dihydroxyethyl)amino-2,4-dichloro-1,3,5-triazine UNIV FUJIAN TECHNOLOGY 2012-10-17 CN disclosed