Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.61 |
| ▸ | MTOR | P42345 | 9/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27863336 | 0.89 | PIK3CA (0.63) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL116045 | 0.87 | PIK3CA (0.79) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| Trifluoroacetic Acid SCHEMBL115353 | 0.81 | PIK3CA (0.70) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL14806834 | 0.79 | PIK3CA (0.67) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL27863274 | 0.78 | PIK3CA (0.64) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL114134 | 0.77 | PIK3CA (0.81) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL114570 | 0.76 | PIK3CA (0.80) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL113887 | 0.74 | PIK3CA (0.81) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL113600 | 0.73 | PIK3CA (0.78) | PIK3CAMTOR | |
| SCHEMBL114911 | 0.72 | PIK3CA (0.78) | PIK3CAMTORPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102548984-A | Inhibitors of PI3 kinase and / or MTOR | AMGEN INC | 2012-07-04 | — | — | CN | disclosed |