Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CPA3 | P15088 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331235 | 0.90 | PPARG (0.49) | FOLH1PPARGEPHX2PPARACPA3 | |
| SCHEMBL429946 | 0.85 | FOLH1 (0.70) | FOLH1CPB2CPA3CYP1A2 | |
| Hydrochloric Acid SCHEMBL30239113 | 0.83 | FOLH1 (0.68) | FOLH1CPB2CPA3CYP1A2 | |
| SCHEMBL4619329 | 0.83 | PPARG (0.55) | FOLH1CPB2PPARGEPHX2PPARA | |
| SCHEMBL4663230 | 0.82 | CYP1A2 (0.65) | FOLH1CPB2PPARGEPHX2PPARA | |
| Hydrochloric Acid SCHEMBL7990559 | 0.81 | PPARG (0.54) | FOLH1PPARGEPHX2PPARACPA3 | |
| SCHEMBL28807890 | 0.81 | PPARA (0.55) | FOLH1PPARGEPHX2PPARAKMT2A | |
| SCHEMBL28947373 | 0.81 | PPARA (0.55) | FOLH1PPARGEPHX2PPARAKMT2A | |
| SCHEMBL28807919 | 0.81 | PPARA (0.55) | FOLH1PPARGEPHX2PPARAKMT2A | |
| SCHEMBL28807881 | 0.81 | PPARA (0.55) | FOLH1PPARGEPHX2PPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102786482-A | Akt protein kinase inhibitors | ARRAY BIOPHARMA INC | 2012-11-21 | — | — | CN | disclosed |