Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 10/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760066 | 0.87 | HDAC1 (0.47) | HDAC2HDAC1HDAC3HDAC10HDAC11 | |
| SCHEMBL27676949 | 0.82 | HDAC2 (0.57) | HDAC2HDAC1HDAC3HDAC10HDAC11 | |
| SCHEMBL296986 | 0.82 | HDAC2 (0.59) | HDAC2HDAC1HDAC3HDAC10HDAC11 | |
| SCHEMBL296987 | 0.82 | HDAC2 (0.59) | HDAC2HDAC1HDAC3HDAC10HDAC11 | |
| SCHEMBL27676960 | 0.80 | HDAC1 (0.57) | HDAC2HDAC1HDAC3HDAC10HDAC11 | |
| SCHEMBL27725335 | 0.78 | HDAC1 (0.53) | HDAC2HDAC1HDAC3HDAC10HDAC11 | |
| SCHEMBL27676947 | 0.78 | HDAC1 (0.53) | HDAC2HDAC1HDAC3HDAC10HDAC11 | |
| SCHEMBL27725365 | 0.76 | HDAC1 (0.51) | HDAC2HDAC1HDAC3HDAC10HDAC11 | |
| SCHEMBL28769333 | 0.74 | HDAC1 (0.51) | HDAC2HDAC1HDAC3HDAC10HDAC11 | |
| SCHEMBL27725142 | 0.73 | HDAC1 (0.52) | HDAC2HDAC1HDAC3HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1926103-B | Sulfonyl pyrroles as HDAC inhibitors | 4SC AG | 2012-12-19 | — | — | CN | claimed |
| CN-1926103-A | Sulfonyl pyrroles as HDAC inhibitors | ALTANA PHARMA AG (DE) | 2007-03-07 | — | — | CN | claimed |