Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.71 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.59 |
| ▸ | PREP | P48147 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27903122 | 0.90 | DPP4 (0.71) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL27754785 | 0.88 | DPP4 (0.67) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL27754514 | 0.86 | DPP4 (0.68) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL27755075 | 0.85 | DPP4 (0.70) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL27734490 | 0.84 | DPP4 (0.55) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL27960029 | 0.83 | DPP4 (1.00) | DPP4DPP8PREP | |
| Oxalic Acid SCHEMBL27886254 | 0.83 | DPP4 (1.00) | DPP4DPP8PREP | |
| Oxalic Acid SCHEMBL27960037 | 0.81 | DPP4 (0.66) | DPP4DPP8 | |
| SCHEMBL27886262 | 0.81 | DPP4 (0.97) | DPP4DPP8PREP | |
| Oxalic Acid SCHEMBL27734267 | 0.80 | DPP4 (0.65) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850330-B | Method for preparing N-substituted pyrrolidine derivative through bromination | DIAO PHARMACEUTICAL GROUP CO., LTD., CHENGDU (CN) | 2014-10-15 | — | — | CN | disclosed |
| CN-102838589-B | Method for preparing N substituted pyrrolidine derivative through acylation of methyl sulfone chloride | CHENGDU DIAO PHARMACY GROUP CO LTD | 2014-03-26 | — | — | CN | disclosed |
| CN-102850330-A | Method for preparing N-substituted pyrrolidine derivative through bromination | CHENGDU DIAO PHARMACY GROUP CO LTD | 2013-01-02 | — | — | CN | disclosed |