Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27904499 | 1.00 | ADORA2A (0.76) | ADORA2AADORA3ADORA2BADORA1PDE10A | |
| SCHEMBL27887645 | 1.00 | ADORA2A (0.76) | ADORA2AADORA3ADORA2BADORA1PDE10A | |
| SCHEMBL2555841 | 0.86 | ADORA2A (1.00) | ADORA2AADORA3ADORA2BADORA1PDE10A | |
| SCHEMBL2555844 | 0.86 | ADORA2A (1.00) | ADORA2AADORA3ADORA2BADORA1PDE10A | |
| SCHEMBL2542194 | 0.85 | ADORA2A (0.70) | ADORA2AADORA3ADORA2BADORA1PDE10A | |
| SCHEMBL2548740 | 0.85 | ADORA2A (0.70) | ADORA2AADORA3ADORA2BADORA1PDE10A | |
| SCHEMBL2555110 | 0.80 | ADORA2A (0.76) | ADORA2AADORA3ADORA2BADORA1PDE10A | |
| SCHEMBL2555106 | 0.80 | ADORA2A (0.76) | ADORA2AADORA3ADORA2BADORA1PDE10A | |
| SCHEMBL2556664 | 0.80 | ADORA2A (0.76) | ADORA2AADORA3ADORA2BADORA1PDE10A | |
| SCHEMBL2550783 | 0.76 | ADORA2A (0.79) | ADORA2AADORA3ADORA2BADORA1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102892761-A | 4 - aminopyrimidine derivatives and their as as adenosine a2a receptor antagonists | PALOBIOFARMA SL | 2013-01-23 | — | — | CN | disclosed |