Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclooctane SCHEMBL21693719 | 1.00 | TDP1 (0.81) | TDP1 | |
| Tert-Butyl Formate SCHEMBL30378535 | 0.90 | TDP1 (1.00) | TDP1 | |
| Tert-Butyl Formate SCHEMBL1671 | 0.90 | — | — | |
| Tert-Butyl Formate SCHEMBL9398245 | 0.87 | — | — | |
| Tert-Butyl Formate SCHEMBL4984399 | 0.87 | — | — | |
| Tert-Butyl Formate SCHEMBL15687802 | 0.87 | — | — | |
| Tert-Butyl Formate SCHEMBL28465801 | 0.87 | — | — | |
| Tert-Butyl Formate SCHEMBL17956883 | 0.86 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL21925517 | 0.84 | — | — | |
| Tert-Butyl Formate SCHEMBL28884208 | 0.81 | TDP1 (0.81) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209470-A | 6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection | HOFFMANN LA ROCHE | 2015-12-30 | — | — | CN | disclosed |
| CN-102918043-B | pyrrolopyrimidine compounds as CDK4/6 inhibitors | NOVARTIS AG (CH) | 2015-07-29 | — | — | CN | disclosed |
| CN-102918043-A | Pyrrolopyrimidine compounds as CDK4/6 inhibitors | NOVARTIS AG | 2013-02-06 | — | — | CN | disclosed |