Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.93 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.93 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.93 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.93 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.93 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787791 | 0.92 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2785372 | 0.92 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2773411 | 0.92 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2771449 | 0.90 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2770829 | 0.89 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2771100 | 0.89 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2788402 | 0.88 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2789921 | 0.86 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2769822 | 0.86 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2770386 | 0.84 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |