Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 20/20 | 0.84 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.72 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.72 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636999 | 0.91 | PIK3CB (1.00) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1639383 | 0.87 | PIK3CB (1.00) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1638086 | 0.85 | PIK3CB (1.00) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1639356 | 0.84 | PIK3CB (1.00) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1639423 | 0.84 | PIK3CB (0.86) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1638468 | 0.84 | PIK3CB (1.00) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1636910 | 0.84 | PIK3CB (1.00) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1639174 | 0.82 | PIK3CB (1.00) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1639432 | 0.82 | PIK3CB (0.82) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1637085 | 0.82 | PIK3CB (1.00) | PIK3CBPIK3CDPIK3CAPIK3CGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712615-A | Chromenone Derivatives with Antitumor Activity | ASTRAZENECA AB | 2012-10-03 | — | — | CN | disclosed |