Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | HASPIN | Q8TF76 | 8/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKACG | P22612 | 1/20 | 0.46 |
| ▸ | PRKACB | P22694 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17502378 | 0.89 | HASPIN (0.59) | DYRK1AHASPINDYRK2 | |
| SCHEMBL17517490 | 0.89 | HASPIN (0.55) | DYRK1AHASPINDYRK2 | |
| SCHEMBL17502370 | 0.88 | HASPIN (0.57) | DYRK1AHASPINDYRK2 | |
| SCHEMBL17502356 | 0.88 | HASPIN (0.57) | DYRK1AHASPINDYRK2 | |
| SCHEMBL17502367 | 0.88 | HASPIN (0.57) | DYRK1AHASPINDYRK2 | |
| SCHEMBL17502369 | 0.88 | HASPIN (0.57) | DYRK1AHASPINDYRK2 | |
| SCHEMBL17502359 | 0.88 | HASPIN (0.57) | DYRK1AHASPINDYRK2 | |
| SCHEMBL17502376 | 0.88 | HASPIN (0.57) | DYRK1AHASPINDYRK2 | |
| SCHEMBL20340614 | 0.86 | DYRK1A (0.53) | MCL1DYRK1AHASPINDYRK2 | |
| SCHEMBL27899833 | 0.86 | DYRK1A (0.55) | DYRK1AHASPINSRCPRKACAPRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146080-B | Beta-carboline alkali derivative compounds and application thereof | XINJIANG HUASHIDAN PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | claimed |
| CN-104755078-A | Application of harmine derivatives in preparation of antimicrobial agents | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2015-07-01 | — | — | CN | disclosed |
| CN-101429198-B | Banisterine derivant and uses thereof | XINJIANG HUASHIDAN MEDICAMENTS RES CO LTD | 2013-10-23 | — | — | CN | disclosed |
| CN-103070862-A | Application of harmine derivative in preparation of antibacterial drugs | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2013-05-01 | — | — | CN | disclosed |