Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 16/20 | 0.65 |
| ▸ | ERBB4 | Q15303 | 4/20 | 0.58 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27893989 | 1.00 | EGFR (0.66) | EGFRERBB2ERBB4ERBB3 | |
| SCHEMBL27893965 | 0.94 | EGFR (0.64) | EGFRERBB2 | |
| SCHEMBL27911104 | 0.94 | EGFR (0.65) | EGFRERBB2 | |
| SCHEMBL27911107 | 0.94 | EGFR (0.66) | EGFRERBB2 | |
| SCHEMBL14854926 | 0.92 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL14855197 | 0.92 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL14854924 | 0.92 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL14855198 | 0.92 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL27893964 | 0.92 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL14854674 | 0.91 | EGFR (0.64) | EGFRERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | claimed |
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | disclosed |