Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.51 |
| ▸ | STK4 | Q13043 | 6/20 | 0.50 |
| ▸ | STK3 | Q13188 | 3/20 | 0.50 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911181 | 0.92 | STK3 (0.59) | EGFRSTK4STK3ERBB2SRC | |
| SCHEMBL27893924 | 0.91 | STK4 (0.62) | EGFRSTK4STK3ERBB2SRC | |
| SCHEMBL28804928 | 0.91 | EGFR (0.63) | EGFRSTK3ERBB2SRCKDR | |
| SCHEMBL14854663 | 0.90 | STK3 (0.64) | EGFRSTK4STK3ERBB2SRC | |
| SCHEMBL27893921 | 0.90 | EGFR (0.55) | EGFRSTK4STK3ERBB2SRC | |
| SCHEMBL27894009 | 0.88 | EGFR (0.56) | EGFRSTK4STK3ERBB2SRC | |
| SCHEMBL27893975 | 0.87 | EGFR (0.48) | EGFRSTK4STK3ERBB2SRC | |
| SCHEMBL27893963 | 0.87 | EGFR (0.52) | EGFRSTK4STK3ERBB2SRC | |
| SCHEMBL27893927 | 0.87 | EGFR (0.55) | EGFRSTK4STK3ERBB2SRC | |
| SCHEMBL27911215 | 0.86 | STK3 (0.47) | EGFRSTK4STK3ERBB2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | claimed |
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | disclosed |