Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69486 | 0.98 | KDM4E (0.55) | KDM4EUSP30CPB1CPB2LMNA | |
| SCHEMBL27692944 | 0.85 | KDM4E (0.55) | KDM4EUSP30 | |
| SCHEMBL27911750 | 0.84 | KDM4E (0.47) | KDM4E | |
| SCHEMBL9672218 | 0.84 | KDM4E (0.47) | KDM4E | |
| SCHEMBL1879655 | 0.84 | KDM4E (0.50) | KDM4E | |
| SCHEMBL24812338 | 0.84 | KDM4E (0.45) | KDM4EUSP30CPB1CPB2 | |
| SCHEMBL1079993 | 0.84 | ADA (0.50) | KDM4EUSP30CPB1CPB2 | |
| SCHEMBL28770737 | 0.83 | KDM4E (0.50) | KDM4E | |
| SCHEMBL4423411 | 0.82 | KDM4E (0.55) | KDM4E | |
| SCHEMBL2174602 | 0.82 | KDM4E (0.48) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985439-B9 | IAP BIR domain binding compounds | 制药科学股份有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-102985439-B | IAP BIR domain binding compounds | 制药科学股份有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-102985439-A | IAP BIR domain binding compounds | AEGERA THERAPEUTICS INC | 2013-03-20 | — | — | CN | disclosed |