Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521996 | 0.95 | TSHR (0.65) | TSHRSMPD1PLA2G4BGGPS1THRA | |
| SCHEMBL4663093 | 0.95 | TSHR (0.65) | TSHRSMPD1PLA2G4BGGPS1THRA | |
| SCHEMBL1522035 | 0.95 | TSHR (0.65) | TSHRSMPD1PLA2G4BGGPS1THRA | |
| SCHEMBL9149380 | 0.95 | TSHR (0.65) | TSHRSMPD1PLA2G4BGGPS1THRA | |
| SCHEMBL10477053 | 0.93 | TSHR (0.62) | TSHRSMPD1PLA2G4BGGPS1LTA4H | |
| SCHEMBL255565 | 0.88 | TSHR (0.54) | TSHRPLA2G4BTHRBLTA4HKMT2A | |
| SCHEMBL30167692 | 0.88 | TSHR (0.54) | TSHRPLA2G4BTHRBLTA4HKMT2A | |
| SCHEMBL255563 | 0.83 | KMT2A (0.54) | TSHRKMT2ACYSLTR1MAOB | |
| SCHEMBL6677146 | 0.82 | TSHR (0.76) | TSHRSMPD1PLA2G4BGGPS1THRA | |
| SCHEMBL17138169 | 0.82 | TSHR (0.76) | TSHRSMPD1PLA2G4BGGPS1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102973417-A | Pharmaceutical and cosmetic compositions containing oxy group-bearing aromatic aldehydes | CUTANIX CORP | 2013-03-20 | — | — | CN | disclosed |