Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28101095 | 0.81 | KMT2A (0.38) | CA1CA2CA9SMN1; SMN2KMT2A | |
| Dimethyl Sulfone SCHEMBL28088209 | 0.78 | CA1 (0.40) | PGRCA1CA2CA9SMN1; SMN2 | |
| SCHEMBL1878004 | 0.76 | CA1 (0.46) | CA1CA2LMNACA4SRC | |
| SCHEMBL9443206 | 0.74 | CA1 (0.44) | CA1CA2LMNACA4SRC | |
| SCHEMBL3900141 | 0.73 | CA4 (0.46) | CA1CA2SMN1; SMN2LMNACA4 | |
| SCHEMBL852436 | 0.72 | ORAI1 (0.41) | CA1CA2CA9SMN1; SMN2CA4 | |
| Ammonia Solution, Strong SCHEMBL9443078 | 0.72 | CA1 (0.43) | CA1CA2LMNACA4SRC | |
| SCHEMBL9443046 | 0.72 | CA1 (0.43) | CA1CA2LMNACA4SRC | |
| SCHEMBL9443233 | 0.72 | CA1 (0.43) | CA1CA2LMNACA4SRC | |
| SCHEMBL28120446 | 0.71 | ELANE (0.40) | CA1CA2LMNACA4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761834-A | Storage stable epoxy resin composition | 澳泽化学特罗斯特贝格有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-105814048-B | Fused tricyclic benzimidizole derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-105188380-B | LXR conditioning agents | 百时美施贵宝公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-105814048-A | Fused tricyclic imidazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-103002735-A | Modulators of 5-ht receptors and methods of use thereof | ABBVI CO | 2013-03-27 | — | — | CN | disclosed |