Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321954 | 0.98 | HRH3 (0.50) | HRH3LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL10629084 | 0.98 | HRH3 (0.50) | HRH3LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL16353683 | 0.95 | KDM4E (0.42) | HRH3LTA4HKDM4EHTT | |
| SCHEMBL16353721 | 0.95 | KDM4E (0.42) | HRH3LTA4HKDM4EHTT | |
| SCHEMBL16353732 | 0.93 | HRH3 (0.46) | HRH3PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL16353799 | 0.93 | HRH3 (0.46) | HRH3PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL964827 | 0.90 | — | — | |
| SCHEMBL7110089 | 0.84 | HRH3 (0.55) | HRH3LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL7307148 | 0.83 | HRH3 (0.44) | HRH3LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL24059343 | 0.81 | HRH3 (0.60) | HRH3LTA4HPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149666-A1 | METHODS FOR TREATING NEOPLASIA | MEDEXIS S.A. (GR) | 2010-12-29 | — | — | WO | claimed |
| EP-0688786-B1 | New hydrazino and hydroxyamino-14beta-hydroxyandrostane derivatives active on the cardio-vascular system, processes for their preparation and pharmaceutical compositions containing same | SIGMA TAU IND FARMACEUTI (IT) | 1997-08-06 | — | — | EP | claimed |
| WO-2010149666-A1 | METHODS FOR TREATING NEOPLASIA | MEDEXIS S.A. (GR) | 2010-12-29 | — | — | WO | disclosed |
| EP-0688786-B1 | New hydrazino and hydroxyamino-14beta-hydroxyandrostane derivatives active on the cardio-vascular system, processes for their preparation and pharmaceutical compositions containing same | SIGMA TAU IND FARMACEUTI (IT) | 1997-08-06 | — | — | EP | disclosed |
| US-5599806-A | CARDIOVASCULAR DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1997-02-04 | — | — | US | disclosed |
| EP-0688786-A1 | New hydrazino and hydroxyamino-14beta-hydroxyandrostane derivatives active on the cardio-vascular system, processes for their preparation and pharmaceutical compositions containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1995-12-27 | — | — | EP | disclosed |
| EP-0094065-B1 | 2-AMINOBENZOIC ACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | FERRER INTERNACIONAL, S.A. (ES) | 1989-12-20 | — | — | EP | disclosed |
| US-4767767-A | ANALGESIC, ANTIINFLAMMATORY AGENT | FERRER INTERNACIONAL S.A. (ES) | 1988-08-30 | — | — | US | disclosed |
| EP-0087856-B1 | A PROCESS FOR THE REMOVAL OF H2S FROM GASEOUS MIXTURES USING DIAMINOETHERS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-02-26 | — | — | EP | disclosed |
| EP-0094065-A2 | 2-Aminobenzoic acid derivatives, a process for their preparation and pharmaceutical compositions | FERRER INTERNACIONAL, S.A. (ES) | 1983-11-16 | — | — | EP | disclosed |