Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | CYCS | P99999 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186744 | 0.85 | STAT3 (0.55) | STAT3STAT1CYP19A1MEN1KMT2A | |
| SCHEMBL8186746 | 0.85 | STAT3 (0.55) | STAT3STAT1CYP19A1MEN1KMT2A | |
| SCHEMBL27964560 | 0.85 | STAT3 (0.76) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL10719623 | 0.84 | STAT3 (0.57) | STAT3STAT1CYP19A1MEN1KMT2A | |
| SCHEMBL8347099 | 0.82 | NPC1 (0.54) | STAT3STAT1CYP19A1MEN1KMT2A | |
| SCHEMBL1224432 | 0.82 | STAT3 (0.86) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL30293296 | 0.82 | STAT3 (0.86) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL31550992 | 0.82 | STAT3 (0.86) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL31324940 | 0.81 | STAT3 (0.84) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL31324939 | 0.81 | STAT3 (0.84) | STAT3STAT1TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102180883-B | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2013-04-17 | — | — | CN | disclosed |