Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.69 |
| ▸ | NQO2 | P16083 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RGS17 | Q9UGC6 | 2/20 | 0.45 |
| ▸ | RGS12 | O14924 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31425123 | 1.00 | TDP1 (0.69) | TDP1NQO2CYP19A1ACHEKDM4E | |
| SCHEMBL10132870 | 0.87 | CYP19A1 (0.56) | TDP1NQO2CYP19A1ACHEKDM4E | |
| SCHEMBL25914855 | 0.82 | TDP1 (1.00) | TDP1NQO2CYP19A1ACHEKDM4E | |
| SCHEMBL10633372 | 0.80 | TDP1 (0.57) | TDP1NQO2CYP19A1ACHEALDH1A1 | |
| SCHEMBL30483850 | 0.77 | TDP1 (0.70) | TDP1NQO2CYP19A1ACHEALDH1A1 | |
| SCHEMBL10132618 | 0.72 | CYP19A1 (0.48) | TDP1NQO2CYP19A1ACHEKDM4E | |
| SCHEMBL25914854 | 0.72 | TDP1 (0.80) | TDP1NQO2CYP19A1KDM4EALDH1A1 | |
| SCHEMBL10132638 | 0.71 | CYP19A1 (0.47) | TDP1NQO2CYP19A1ACHEKDM4E | |
| SCHEMBL422412 | 0.70 | CYP19A1 (0.47) | TDP1NQO2CYP19A1ACHEKDM4E | |
| SCHEMBL10132627 | 0.70 | CYP19A1 (0.47) | TDP1NQO2CYP19A1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119432631-A | Recombinant bacterium and application thereof in production of benzophenanthridine alkaloids | 陈云 | 2025-02-14 | — | — | CN | disclosed |
| CN-111560016-A | Method for extracting and separating coptisine from celandine | 郑州铁路职业技术学院 | 2020-08-21 | — | — | CN | disclosed |
| CN-103059037-B | A kind of method of Chelidonine in enriching and purifying greater celandine | Daxing'an Mountainrange Lin Gebei psychrophile Science and Technology Co., Ltd. (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-103059037-A | Method for enriching and purifying chelidonine in celandine | DAXINGANLING LINGONBERRY ORGANIC FOODSTUFFS CO LTD | 2013-04-24 | — | — | CN | disclosed |