Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | ATM | Q13315 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | GAA | P10253 | 4/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.80 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15236158 | 0.84 | GLA (0.73) | GLAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL15227898 | 0.81 | GLA (0.74) | GLAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL15227895 | 0.81 | GLA (0.74) | GLAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL3621970 | 0.80 | GLA (0.66) | GLAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL8600513 | 0.80 | GLA (0.66) | GLAKDM4EMAPTMEN1KMT2A | |
| Water SCHEMBL27633216 | 0.78 | GLA (0.64) | GLAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL1736463 | 0.78 | GLA (0.63) | GLAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL1736464 | 0.78 | GLA (0.63) | GLAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL28236277 | 0.77 | KDM4E (0.63) | GLAKDM4EMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1736894 | 0.77 | GLA (0.62) | GLAKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429198-B | Banisterine derivant and uses thereof | XINJIANG HUASHIDAN MEDICAMENTS RES CO LTD | 2013-10-23 | — | — | CN | disclosed |
| CN-103070862-A | Application of harmine derivative in preparation of antibacterial drugs | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2013-05-01 | — | — | CN | disclosed |