Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 11/20 | 0.58 |
| ▸ | PPIB | P23284 | 6/20 | 0.58 |
| ▸ | PPIG | Q13427 | 4/20 | 0.58 |
| ▸ | PPIA | P62937 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15939528 | 0.77 | PPID (0.65) | PPIDPPIBPPIGPPIAEPHX1 | |
| SCHEMBL15652114 | 0.76 | PPID (0.65) | PPIDPPIBPPIGPPIAEPHX1 | |
| SCHEMBL12643760 | 0.75 | PPID (0.63) | PPIDPPIBPPIGPPIAEPHX1 | |
| SCHEMBL6824244 | 0.75 | CYP3A4 (0.66) | PPIDPPIBPPIGPPIAEPHX2 | |
| SCHEMBL27900091 | 0.74 | PPID (0.46) | PPIDPPIBPPIGPPIAMEN1 | |
| SCHEMBL2044119 | 0.73 | PPID (1.00) | PPIDPPIBPPIGPPIAEPHX1 | |
| SCHEMBL27900153 | 0.73 | PPID (0.48) | PPIDPPIBPPIGPPIAMEN1 | |
| SCHEMBL27900124 | 0.71 | PPID (0.46) | PPIDPPIBPPIGPPIAMEN1 | |
| SCHEMBL19882140 | 0.71 | PPID (0.58) | PPIDPPIBPPIGPPIAEPHX1 | |
| SCHEMBL12643755 | 0.71 | SMN1; SMN2 (0.68) | PPIDPPIBPPIGPPIAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102811998-A | Novel cyclophilin inhibitors and uses thereof | INST NAT SANTE RECH MED | 2012-12-05 | — | — | CN | disclosed |