Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.45 |
| ▸ | PRKDC | P78527 | 4/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | HCK | P08631 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.45 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 3/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900223 | 0.93 | PIK3CD (0.49) | PIK3CDPIK3CGPRKDCEGFRPIK3CA | |
| SCHEMBL27899970 | 0.92 | BTK (0.48) | PIK3CDPIK3CGPRKDCEGFRPIK3CA | |
| SCHEMBL27900039 | 0.91 | PIK3C2B (0.53) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C2B | |
| SCHEMBL27882483 | 0.91 | PIK3C2B (0.56) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C2B | |
| SCHEMBL27900064 | 0.90 | PIK3CD (0.52) | PIK3CDPIK3CGPRKDCEGFRPIK3CA | |
| SCHEMBL27899982 | 0.89 | PIK3CD (0.51) | PIK3CDPIK3CGPRKDCEGFRPIK3CA | |
| SCHEMBL28065734 | 0.88 | PIK3CD (0.51) | PIK3CDPIK3CGPRKDCEGFRPIK3CA | |
| SCHEMBL27900032 | 0.87 | PIK3CD (0.47) | PIK3CDPIK3CGPRKDCEGFRPIK3CA | |
| SCHEMBL27882527 | 0.86 | PIK3CG (0.47) | PIK3CDPIK3CGPRKDCEGFRPIK3CA | |
| SCHEMBL28065660 | 0.85 | PIK3CG (0.54) | PIK3CDPIK3CGPRKDCEGFRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102812013-B | Novel benzopyran kinase modulators | RHIZEN PHARMACEUTICALS S.A. (CH) | 2016-05-25 | — | — | CN | claimed |
| CN-102812013-A | Novel Benzopyran Kinase Modulators | INCOZEN THERAPEUTICS PVT LTD | 2012-12-05 | — | — | CN | claimed |
| CN-102812013-B | Novel benzopyran kinase modulators | RHIZEN PHARMACEUTICALS S.A. (CH) | 2016-05-25 | — | — | CN | disclosed |
| CN-102812013-A | Novel Benzopyran Kinase Modulators | INCOZEN THERAPEUTICS PVT LTD | 2012-12-05 | — | — | CN | disclosed |