Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046202 | 0.94 | TAAR1 (0.50) | TAAR1HTR2AMAPK1NPC1NFKB1 | |
| SCHEMBL15351972 | 0.91 | TAAR1 (0.48) | TAAR1HTR2AHMOX1ALDH1A1SIGMAR1 | |
| SCHEMBL1045906 | 0.91 | TAAR1 (0.48) | TAAR1HTR2AHMOX1ALDH1A1SIGMAR1 | |
| SCHEMBL15351540 | 0.91 | TAAR1 (0.48) | TAAR1HTR2AHMOX1ALDH1A1SIGMAR1 | |
| SCHEMBL15353356 | 0.91 | TAAR1 (0.48) | TAAR1HTR2AHMOX1ALDH1A1SIGMAR1 | |
| SCHEMBL15352000 | 0.91 | TAAR1 (0.48) | TAAR1HTR2AHMOX1ALDH1A1SIGMAR1 | |
| SCHEMBL15352255 | 0.91 | TAAR1 (0.48) | TAAR1HTR2AHMOX1ALDH1A1SIGMAR1 | |
| SCHEMBL15351195 | 0.91 | TAAR1 (0.48) | TAAR1HTR2AHMOX1ALDH1A1SIGMAR1 | |
| SCHEMBL1005011 | 0.87 | TAAR1 (0.52) | TAAR1HTR2AMAPK1NPC1NFKB1 | |
| SCHEMBL7904900 | 0.82 | TAAR1 (0.62) | TAAR1HTR2AMAPK1NPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101277740-B | Antituberculous composition comprising azole compound | OTSUKA PHARMA CO LTD | 2012-12-05 | — | — | CN | disclosed |