Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001651 | 0.99 | TLR4 (0.71) | TLR4KMT2ALMNAMAPTTRPV1 | |
| SCHEMBL2001649 | 0.99 | TLR4 (0.71) | TLR4KMT2ALMNAMAPTTRPV1 | |
| SCHEMBL871358 | 0.89 | TLR4 (0.73) | TLR4KMT2ALMNAMAPTTRPV1 | |
| SCHEMBL872918 | 0.88 | TLR4 (0.58) | TLR4LMNANPC1HTTMRGPRX1 | |
| SCHEMBL6229405 | 0.88 | TLR4 (0.58) | TLR4KMT2AMAPTNPC1MRGPRX1 | |
| SCHEMBL28159349 | 0.88 | TLR4 (0.58) | TLR4LMNANPC1HTTMRGPRX1 | |
| SCHEMBL872114 | 0.88 | TLR4 (0.81) | TLR4KMT2ALMNAMAPTTRPV1 | |
| SCHEMBL27592236 | 0.86 | TLR4 (0.56) | TLR4KMT2ALMNAMAPTNPC1 | |
| SCHEMBL28159329 | 0.86 | TLR4 (0.55) | TLR4KMT2AMAPTL3MBTL1GAA | |
| SCHEMBL27985634 | 0.85 | TLR4 (0.56) | TLR4LMNAALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102821763-A | Compound for inhibiting peripheral nerve disorder induced by anticancer agent | TAKEDA PHARMACEUTICAL | 2012-12-12 | — | — | CN | disclosed |
| CN-102670503-A | Stable emulsion composition | TAKEDA PHARMACEUTICAL | 2012-09-19 | — | — | CN | disclosed |
| CN-1416341-B | Stable emulsion compositions | TAKEDA CHEMICAL INDUSTRIES LTD | 2010-05-05 | — | — | CN | disclosed |
| CN-101212986-A | stable emulsified composition | TAKEDA PHARMACEUTICAL (JP) | 2008-07-02 | — | — | CN | disclosed |
| CN-1416341-A | Stable emulsion compsns | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-07 | — | — | CN | disclosed |