Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.74 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900616 | 0.87 | HCRTR1 (0.74) | HCRTR1HCRTR2 | |
| SCHEMBL1671272 | 0.85 | HCRTR1 (1.00) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL11908613 | 0.84 | HCRTR1 (0.79) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL1671671 | 0.82 | HCRTR1 (1.00) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL1671471 | 0.81 | HCRTR1 (0.76) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL1671677 | 0.81 | HCRTR1 (1.00) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL27883254 | 0.80 | HCRTR1 (0.75) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL11907998 | 0.80 | HCRTR1 (1.00) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL30465896 | 0.80 | HCRTR1 (1.00) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL1672159 | 0.79 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781942-A | Disubstituted octahy-dropyrrolo [3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV | 2012-11-14 | — | — | CN | claimed |