SCHEMBL27900930

SCHEMBL27900930

CCn1c2ccc(Br)cc2c2cc(C(C)=O)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.55
HPGD P15428 5/20 0.55
HTT P42858 2/20 0.55
ALDH1A1 P00352 4/20 0.51
MAPT P10636 7/20 0.49
LMNA P02545 3/20 0.49
TSPO P30536 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48
DNM1 Q05193 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
PPARG P37231 1/20 0.43
NCOA2 Q15596 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
MAPK1 P28482 1/20 0.43
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153044 0.91 KDM4E (0.65) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL29540056 0.91 KDM4E (0.65) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL16097569 0.88 HPGD (0.57) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL13320187 0.86 KDM4E (0.50) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL27918847 0.86 CNR2 (0.52) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL27918794 0.85 HPGD (0.49) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL2735111 0.84 KDM4E (0.58) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL871702 0.83 MAPT (0.55) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL29429155 0.83 MAPT (0.55) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL13539146 0.83 KDM4E (0.56) KDM4EHPGDHTTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103333678-A One and two-photon mitochondrion fluorescence probe and application thereof UNIV SHANDONG 2013-10-02 CN disclosed
CN-103087706-A Single/double-photon acidic cell organelle fluorescent probe and application thereof UNIV SHANDONG 2013-05-08 CN disclosed